The GKF 720 HiProtect provides a high containment concept for the production of potent and costly niche products such as "orphan drugs” against rare diseases.

The HiProTect platform offers all features and functionalities from the GKF 720. It offers a washable containment concept (WIP) ensuring highest protection class for operators, up to OEB 5 product requirements (0.1 µg/m³). The GKF 720 HiProTect is able to produce small batches for research and development or clinical trial supplies.

Containment solution for high potent pharmaceuticals.

The GKF 720 HiProtect is equipped with inflatable door-sealings and provides a controlled and monitored negative pressure in the product handling area. Accesssibility can be ensured through glove ports and rapid transfer ports (RTP). Air inlet and air outlet HEPA filters are given.

Materials, design and cleaning appliances have been selected to achieve best in class cleaning results, in order to avoid cross-contamination from product to product and operator exposure.

The first step of the cleaning cycle is a manual dry suction of product residues via an integrated suction hose. The second step is the automatic wetting system based on an in-built spray nozzle. During the automated wetting process only 200 milliliters of water, in form of fine droplets, binds airborne particles. In the third step a manual wash-down of the processing area takes place, in order to remove last product residue. This can be repeated if necessary.

Special feature: APD technology (automated process development) based on Design of Experiments (DoE)

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